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The 2nd
PSU International Teaching Platform
Tumor Immunology
Jointly
organized by
At The Department of Biomedical Sciences
Faculty of Medicine,
Course Programme:
Course Lectures:
Day 1: Dec. 15, 2003
- Introduction to the Immune System [CF; Lecture 1]
(Innate and adaptive immunity; Dendritic cells and macrophages; T and B lymphocytes;
TCR and immunoglobulins; MHC-restricted presentation; Cytokines; Th1/Th2 balance)
- Tumour biology & immune surveillance [HF; Lecture 2]
(Clinical evidence; Incidence; Relation to age and immunodepression; Experimental models; Tumour antigens)
- Tumor microenvironment [HF; Lecture 3]
(Dendritic cells and T lymphocytes; Cytotoxicity; Macrophages; Cytokines; Th1/Th2 balance;
Regulatory T cells; Cancer models: prostate, lung, colon, uterus)
Day 2: Dec. 16, 2003
- Cytokines and cancer [ET; Lecture 4]
(Physiopathology andimmunotherapy; Gene therapy; Cancer models: bladder, kidney, melanoma, hemato)
- Non-specific cellular therapy [HF; Lecture 5]
(Macrophages, NK and LAK; Cancer models: ovary, bladder, colon, mesothelioma)
- Specific therapy: monoclonal antibodies [CF; Lecture 6]
(Cancer models: breast, lung, lymphoma, LLC)
- Specific therapy: T lymphocytes [HF; Lecture 7]
(Allografts, TIL, T-cell clones)
Day 3: Dec. 17, 2003
- Vaccination anti-tumorale [ET; Lecture 8]
(Mechanisms: dendritic cells, tumour antigens; Clinical trials; Immunomonitoring)
- Epstein-Barr virus- and HPV8-associated peripheral T-cell proliferative disease
- Quantitative analysis of EBV-genome in the plasma of patients with peripheral T-cell proliferative disease
Day 4-6: Dec. 18-20, 2003
Lab course training
1. Immunomonitoring
- Intracellular staining of cytokines
- Detection of specific T lymphocytes
2. Demonstration of detection of tumour antigens by antibodies
3. Exercise session of experimental data in the field of tumour immunology and immunotherapy
Speakers & Instructors:
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1. Hervé Fridman, M.D., Ph.D. |
Prof. of Immunology, Medical School, Université Pierre et Marie Curie – Paris 6 |
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2. Catherine Fridman, Ph.D. |
Prof. of Immunology, Université Paris 6 |
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3. Eric Tartour, M.D., Ph.D. |
Assistant-Prof. of Immunology, Medical School, Université Renée Descartes – Paris 5 |
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4. Sylvie Garcia, Ph.D. |
Investigator, Institut Pasteur |
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5. Adrien Six, Ph.D. |
Assistant-Prof. of Immunology, Institut Pasteur and Université Paris 6 |
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6. Suvina Ratanachaiyavong, M.D., Ph.D. |
Department of Biomedical Sciences, Faculty of Medicine, Prince of Songkla University |
Lecture Course Handout - Supplement: Glossary, Discussion
Lab Course Handout - Supplement