Immunologie Fondamentale


 

Analyses d'articles - Année universitaire 2002-2003 

 

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1.     Lenschow, D. J., Herold, K. C., Rhee, L., Patel, B., Koons, A., Qin, H. Y., Fuchs, E. S.,B, Thompson, C. B. and Bluestone, J. A. (1996) CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity 5, 285-293.

#04304 (pdf; 380Ko)

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2.     Waisman, A., Ruiz, P.J., Hirschberg, D.L., Gelman, A., Oksenberg, J.R., brocke, S., Mor, F., Cohen, I.R. and Steinman, L. (1996) Suppressive vaccination with DNA encoding a variable region gene of the T-cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity. Nat. Med. 2, 899-905.

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3.     Celluzzi, C. M., Mayordomo, J. I., Storkus, W. J., Lotze, M. T. and Falo, L. D., Jr. (1996) Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity. J. Exp. Med. 183, 283-287.

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4.     von der Weid, T., Honarvar, N. and Langhorne, J. (1996) Gene-targeted mice lacking B cells are unable to eliminate a blood stage malaria infection. J. Immunol. 156, 2510-2516.

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5.     Seixas, E. M. G.  and Langhorne, J. (1999) gd T cells contribute to control of chronic parasitemia in Plasmodium chabaudi infections in mice. J. Immunol. 162, 2837-2841.

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6.     Klenerman, P. and Zinkernagel, R.M. (1998) Original antigenic sin impairs cytotoxic T lymphocyte responses to viruses bearing variant epitopes. Nature 394, 482-485.

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7.     Gao, Y., Sun, Y., Frank, K.M., Dikkes, P., Fujiwara, Y., Seidl, K.J., Sekiguchi, J.M., Rathbun, G.A., Swat, W., Wang, J., Bronson, R.T., Malynn, B.A., Bryans, M., Zhu, C., Chaudhuri, J., Davidson, L., Ferrini, R., Stamato, T., Orkin, S.H., Greenberg, M.E. and Alt, F.W. (1998) A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell 95, 891-902.

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8.     Nagata, K., Tanaka, K., Ogawa, K., Kemmotsu, K., Imai, T., Yoshie, O., Abe, H., Tada, K., Nakamura, M., Sugamura, K. and Takano, S. (1999) Selective expression of a novel surface molecule by human Th2 cells in vivo. J. Immunol. 162, 1278-1286.

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9.     Sourdive, D.J.D., Murali-Krishna, K., Altman, J.D., Zajac, A.J., Whitmire, J.K., Pannetier, C., Kourilsky, P., Evavold, B., Sette, A. and Ahmed, R. (1998) Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection. J. Exp. Med. 188, 71-82.

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10.  Stanhope-Baker, P., Hudson, K.M., Shaffer, A.L., Constantinescu, A. and Schlissel, M.S. (1996) Cell type-specific chromatin structure determines the targeting of V(D)J recombinase activity in vitro. Cell 85, 887-897.

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11.  Burdin, N., Brossay, L., Koezuka, Y., Smiley, S. T., Grusby, M. J., Gui, M., Taniguchi, M., Hayakawa, K. and Kronenberg, M. (1998) Selective ability of mouse CD1 to present glycolipids: a-galactosylceramide specifically stimulates Va14+ NK T lymphocytes. J. Immunol. 161, 3271-3281.

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12.  Hung, K., Hayashi, R., Lafond-Walker, A., Lowenstein, C., Pardoll, D. and Levitsky, H. (1998) The central role of CD4+ T cells in the antitumor immune response. J. Exp. Med. 188, 2357-2368.

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13.  Eberl, G., Fehling, H. J., von Boehmer, H. and MacDonald, H. R. (1999) Absolute requirement for the pre-T cell receptor a chain during NK1.1+TCRab cell development. Eur. J. Immunol. 29, 1966-1971.

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14.  Douek, D. C., McFarland, R. D., Keiser, P. H., Gage, E. A., Massey, J. M., Haynes, B. F., Polis, M. A., Haase, A. T., Feinberg, M. B., Sullivan, J. L., Jamieson, B. D., Zack, J. A., Picker, L. J., and Koup, R. A. (1998) Changes in thymic function with age and during the treatment of HIV infection. Nature 396, 690-695.

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15.  Sallusto, F., Lenig, D., Förster, R., Lipp, M., and Lanzavecchia, A. (1999) Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401, 708-711.

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16.  Reinhardt, R. L., Khoruts, A., Merica, R., Zell, T., and Jenkins, M. K. (2001) Visualizing the generation of memory CD4 T cells in the whole body. Nature 410, 101-105.

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17.  Champagne, P., Ogg, G. S., King, A. S., Knabenhans, C., Ellefsen, K., Nobile, M., Appay, V., Rizzardi, G. P., Fleury, S., Lippk, M., Försterk, R., Rowland-Jones, S., Sékaly, R. P., McMichael, A. J., and Pantaleo, G. (2001) Skewed maturation of memory HIV-specific CD8 T lymphocytes. Nature 410, 106-110.

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18.  Lee, P. P., Yee, C., Savage, P. A., Fong, L., Brockstedt, D., Weber, J. S., Johnson, D., Swetter, S., Thompson, J., Greenberg, P. D., Roederer, M., and Davis, M. M. (1999) Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients. Nature Med. 5, 677-685.

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19.  Boileau, C., Houde, M., Dulude, G., Clegg, C. H., and Perreault, C. (2000) Regulation of extrathymic T cell development and turnover by oncostatin M.  J. Immunol. 164, 5713-5720.

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20.  Parrish-Novak, J., Dillon, S. R., Nelson, A., Hammond, A., Sprecher, C., Gross, J.A., Johnston, J., Madden, K., Xu, W. F., West, J., Schrader, S., Burkhead, S., Heipel, M., Brandt, C., Kuijper, J. L., Kramer, J., Conklin, D., Presnell, S. R., Berry, J., Shiota, F., Bort, S., Hambly, K., Mudri, S., Clegg, C., Moore, M., and Foster, D. (2000) Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 408, 57-63.

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21.  Levashina, E. A., Langley, E., Green, C., Gubb, D., Ashburner, M., Hoffmann, J. A., and Reichhart, J. M. (1999) Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila. Science 285, 1917-1919.

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22.  Cui, J., Shin, T., Kawano, T., Sato, H., Kondo, E., Toura, I., Kaneko, Y., Koseki, H., Kanno, M., and Taniguchi, M. (1997) Requirement for Va14 NKT cells in IL-12-mediated rejection of tumors. Science 278, 1623-1626.

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23.  Vicari, A. P., Figueroa, D. J., Hedrick, J. A., Foster, J. S., Singh, K. P., Menon, S., Copeland, N. G., Gilbert, D. J., Jenkins, N. A., Bacon, K. B., and Zlotnik, A. (1997) TECK: a novel CC chemokine specifically expressed by thymic dendritic cells and potentially involved in T cell development. Immunity 7, 291-301.

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24.  Strong, S. J., Mueller, M. G., Litman, R. T., Hawke, N. A., Haire, R. N., Miracle, A. L., Rast, J. P., Amemiya, C. T., and Litman, G. W. (1999) A novel multigene family encodes diversified variable regions. Proc. Natl. Acad. Sci. USA 96, 15080-15085.

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25.  Rothstein, D. M., Livak, M. F., Kishimoto, K., Ariyan, C., Qian, H. Y., Fecteau, S., Sho, M., Deng, S., Zheng, X. X., Sayegh, M. H., and Basadonna, G. P. (2001) Targeting signal 1 through CD45RB synergizes with CD40 ligand blockade and promotes long term engraftment and tolerance in stringent transplant models. J. Immunol. 166, 322-329.

#07575 (pdf; 790Ko)

 

26.  Kaech, S. M.,  and Ahmed, R. (2001) Memory CD8+  T cell differentiation: initial antigen encounter triggers a developmental program in naïve cells. Nature Immunol. 2, 415-422.

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27.  Casellas, R., Shih, T. A., Kleinewietfeld, M., Rakonjac, J., Nemazee, D., Rajewsky, K., and Nussenzweig, M. C. (2001) Contribution of receptor editing to the antibody repertoire. Science 291, 1541-1544.

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28.  Dieckmann, D., Plottner,  H., Berchtold, S., Berger, T., and Schuler, G. (2001) Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood. J. Exp. Med. 193, 1303-1310.

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29.  Geijtenbeek, T. B., Torensma, R., van Vliet, S. J., van Duijnhoven, G. C., Adema, G. J., van Kooyk, Y., and Figdor, C. G. (2000) Identification of DC-SIGN, a novel dendritic cell-specific ICAM-3 receptor that supports primary immune responses. Cell 100, 575-585.

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30.  Greenwald, R. J., Boussiotis, V. A., Lorsbach, R. B., Abbas, A. K., and Sharpe, A. H. (2001) CTLA-4 regulates induction of anergy in vivo. Immunity. 14, 145-155.

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31.  Huang, Q., Liu, D., Majewski, P., Schulte, L. C., Korn, J. M., Young, R. A., Lander, E. S., and Hacohen, N. (2001) The plasticity of dendritic cell responses to pathogens and their components. Science 294, 870-875.

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32.  Irie-Sasaki, J., Sasaki,  T., Matsumoto, W., Opavsky, A., Cheng, M., Welstead, G., Griffiths, E., Krawczyk, C., Richardson, C. D., Aitken, K., Iscove, N., Koretzky, G., Johnson, P., Liu, P., Rothstein, D. M., and Penninger, J. M. (2001) CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature 409, 349-354.

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33.  Jonuleit, H., Schmitt, E., Stassen, M., Tuettenberg, A., Knop, J., and Enk, A. H. (2001) Identification and functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood. J. Exp. Med. 193, 1285-1294.

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34.  Mori, S., Nakano, H., Aritomi, K., Wang, C. R., Gunn, M. D., and Kakiuchi, T. (2001) Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. J. Exp. Med. 193, 207-218.

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35.  Müller, A., Homey, B., Soto, H., Ge, N., Catron, D., Buchanan, M. E., McClanahan, T., Murphy, E., Yuan, W., Wagner, S. N., Barrera, J. L., Mohar, A., Verastegui, E., and Zlotnik, A. (2001) Involvement of chemokine receptors in breast cancer metastasis. Nature 410, 50-56.

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36.  Rogers, P. R., Song, J., Gramaglia, I., Killeen, N., and Croft, M. (2001) OX40 promotes Bcl-xL and Bcl-2 expression and is essential for long-term survival of CD4 T cells. Immunity. 15, 445-455.

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37.  van Stipdonk, M. J., Lemmens, E. E., and Schoenberger, S. P. (2001) Naive CTLs require a single brief period of antigenic stimulation for clonal expansion and differentiation. Nature Immunol. 2, 423-429.

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38.  He, X., Janeway, Jr., C. A., Levine, M., Robinson, E., Preston-Hurlburt, P., Viret, C., and Bottomly, K. (2002) Dual receptor T cells extend the immune repertoire for foreign antigens. Nature Immunol. 3, 127-134.

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39.  Moser, J. M., Gibbs, J., Jensen, P. E., and Lukacher, A. E. (2002) CD94-NKG2A receptors regulate antiviral CD8+ T cell responses.  Nature Immunol. 3, 189-195.

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40.  Suzuki, K., Oida, T., Hamada, H., Hitotsumatsu, O., Watanabe, M., Hibi, T., Yamamoto, H., Kubota, E., Kaminogawa, S., and Ishikawa, H. (2000) Gut cryptopatches: direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis. Immunity. 13, 691-702.

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41.  Lambolez, F., Azogui, O., Joret, A. M., Garcia, C., von Boehmer, H., Di Santo, J., Ezine, S., and Rocha, B. (2002) Characterization of T Cell Differentiation in the Murine Gut. J. Exp. Med. 195, 437-449.

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42.  Kang, J., Volkmann, A., and Raulet, D. H. (2001) Evidence that gd versus ab T cell fate determination is initiated independently of T cell receptor signaling. J. Exp. Med. 193, 689-698.

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43.  Ferrero, I., Wilson, A., Beermann, F., Held, W., and MacDonald, H. R. (2001) T cell receptor specificity is critical for the development of epidermal gd T cells. J. Exp. Med. 194, 1473-1483.

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44.  Cannon, J. P., Haire, R. N., and Litman, G. W. (2002) Identification of diversified genes that contain immunoglobulin-like variable regions in a protochordate. Nat Immunol. 3, 1200-1207.

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45.  Wang, J. H., Nichogiannopoulou, A., Wu, L., Sun, L., Sharpe, A. H., Bigby, M., and Georgopoulos, K. (1996) Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 5, 537-549.

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46.  Serra, P., Amrani, A., Han, B., Yamanouchi, J., Thiessen, S. J., and Santamaria, P. (2002) RAG-dependent peripheral T cell receptor diversification in CD8+ T lymphocytes. Proc.Natl.Acad.Sci.USA 99, 15566-15571.

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47.  Hori, S., Nomura, T., and Sakaguchi, S. (2003) Control of regulatory T cell development by the transcription factor foxp3. Science 299, 1057-1061.

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48.  Pasqual, N., Gallagher, M., Aude-Garcia, C., Loiodice, M., Thuderoz, F., Demongeot, J., Ceredig, R., Marche, P. N., and Jouvin-Marche, E. (2002) Quantitative and qualitative changes in V-Ja rearrangements during mouse thymocytes differentiation: implication for a limited T cell receptor a chain repertoire. J.Exp.Med. 196, 1163-1173.

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49.  Zhang, L., Yu, W., He, T., Yu, J., Caffrey, R. E., Dalmasso, E. A., Fu, S., Pham, T., Mei, J., Ho, J. J., Zhang, W., Lopez, P., and Ho, D. D. (2002) Contribution of human a-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor. Science 298, 995-1000.

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50.  Pasare, C.,  and Medzhitov, R. (2003) Toll Pathway-Dependent Blockade of CD4+CD25+ T Cell-Mediated Suppression by Dendritic Cells. Science 299, 1033-1036.

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#0787 Suppl. (pdf; 500Ko)

 

 

 

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